Absolutely - any simplex contact is valid, and non-chasers are often not bothered about the reference. On 2M FM I often get “I just like to call in to help”.
Last week I was having a mare on Twyn Glas GW/SW-019 with no responses to my CQ’s after the first two QSO’s. I checked the GB3VM and GB3CG repeaters and was getting excellent signals from both, so on each repeater as an ongoing QSO closed I asked “can anyone hear me on the input - if so can we have a quick simplex contact ?” That gained me another 3 QSO’s and a qualification that was beginning to look unlikely.